Intravitreal vascular endothelial growth factor inhibitor systemic and renal toxicity registry
The current database for VEGFi-related nephrotoxicity constitutes the largest case series presented for this condition. This study opens the door for future studies to evaluate what subgroups experience acute kidney injury, proteinuria and hypertension exacerbations. Additionally, we may expand on our database to include timeline markers for symptomatic-correlative VEGFi usage and, in time, predictive measures on a larger scale to correlate comorbidity/drug use with drug effect and mechanism of action.
Authors
- A Massoud
- Michael Kerr (ORCID: https://orcid.org/0000-0002-8533-336X)
- Matthew Nguyen
- Mina Ibrahim Tadros (ORCID: https://orcid.org/0000-0001-7092-8603)
- Rebecca S. Ahdoot
- Vu Q. Nguyen (ORCID: https://orcid.org/0000-0001-7802-8028)
- Ira Kurtz
- Ramy Magdy Hanna (ORCID: https://orcid.org/0000-0003-1807-8909)
- Arzu Çiftçi Demirci (ORCID: https://orcid.org/0000-0002-0431-9807)
- Samir Patel (ORCID: https://orcid.org/0000-0002-4471-2996)
- Tai Truong
- Caroline Gee
- Dao Le (ORCID: https://orcid.org/0000-0002-6782-8203)
- Ryan Evan Fekrat
- Sohrab Kharabaf (ORCID: https://orcid.org/0000-0002-1215-4424)
Institutions
- University of California, Los Angeles (US)
- University of California, Irvine (US)
- Muğla University (TR)
Publication Details
- Journal
- Clinical Kidney Journal
- Published
- 2025-06-27
- DOI
- https://doi.org/10.1093/ckj/sfaf206
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of California, Irvine