Combination of biological aging and genetic risk helps identify at-risk population of thoracic aortic aneurysms: insight from a prospective cohort study of UK Biobank
PhenoAgeAccel has the potential to serve as a novel aging biomarker for identifying high-risk populations of TAA. The combination of PhenoAgeAccel and genetic risk can further improve TAA risk stratification, thereby informing the formulation of screening strategy and primary prevention for TAA.
Authors
- Zhensheng Hu (ORCID: https://orcid.org/0000-0001-5961-5104)
- Yi Zhou (ORCID: https://orcid.org/0000-0002-4774-2234)
- Chaoyu Xie
- Runnan Shen
- Jiatang Xu
- Kai Huang (ORCID: https://orcid.org/0000-0002-6957-880X)
- Yangfan Su
- Hongze Liu
Institutions
- Sun Yat-sen University (CN)
- Sun Yat-sen Memorial Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-06-27
- DOI
- https://doi.org/10.1097/js9.0000000000002898
- Citations
- 2
- Primary Topic
- Aortic aneurysm repair treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.04