Depicting patient-reported outcome measures within directed acyclic graphs: practice and implications for causal reasoning

Multidimensional outcome constructs formed under a formative model increases the complexity of causal analyses. Despite this, multidimensional measures may particularly aid with a variety of 'outcome-wide' studies when assessing exposures that may be beneficial for some outcomes but harmful for others. Thus, we have taken important steps to supporting such studies in observational settings by showing how PROMs can be incorporated into DAGs to inform such causal analyses.

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Publication Details

Journal
Quality of Life Research
Published
2025-06-27
DOI
https://doi.org/10.1007/s11136-025-04007-9
Citations
2
Primary Topic
Health Systems, Economic Evaluations, Quality of Life
Type
article
Field-Weighted Citation Impact
6.26

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article

Depicting patient-reported outcome measures within directed acyclic graphs: practice and implications for causal reasoning

Tessa Peasgood, Peter W. G. Tennant, Matthew Franklin
2 citations
Quality of Life Research
Health Systems, Economic Evaluations, Quality of Life
6.26
article

Depicting patient-reported outcome measures within directed acyclic graphs: practice and implications for causal reasoning

Tessa Peasgood, Peter W. G. Tennant, Matthew Franklin
article en
2 citations

Abstract

Multidimensional outcome constructs formed under a formative model increases the complexity of causal analyses. Despite this, multidimensional measures may particularly aid with a variety of 'outcome-wide' studies when assessing exposures that may be beneficial for some outcomes but harmful for others. Thus, we have taken important steps to supporting such studies in observational settings by showing how PROMs can be incorporated into DAGs to inform such causal analyses.

Quality of Life ResearchVol. 34(8)
Turing Institute (GB), University of Leeds (GB), British Library (GB), University of Sheffield (GB)
National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care Yorkshire and Humber
Good health and well-being
Openalex Percentile: Top 4%
Health Systems, Economic Evaluations, Quality of Life
6.26
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Depicting patient-reported outcome measures within directed acyclic graphs: practice and implications for causal reasoning — Tessa Peasgood, Peter W. G. Tennant, et al. · Quality of Life Research (2025) | TGRS Research Map | TGRS