Pharmacokinetic Characterization of Rituximab in Patients with Glomerular Diseases

Albuminemia and proteinuria affect rituximab t 1/2 and drug exposure in patients with glomerular diseases. Patients with proteinuria >2.4 g /24h may require higher frequent dosing for adequate rituximab exposure. Establishing an optimal dosing regimen in this population remains warranted.

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Publication Details

Journal
Therapeutic Drug Monitoring
Published
2025-06-27
DOI
https://doi.org/10.1097/ftd.0000000000001353
Citations
1
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
Field-Weighted Citation Impact
1.43
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Pharmacokinetic Characterization of Rituximab in Patients with Glomerular Diseases

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Pharmacokinetic Characterization of Rituximab in Patients with Glomerular Diseases

Irene Agraz Pamplona, Sonia García García, Manuel Hernández González, Roger Colobrán, María José Soler, María Larrosa-García, Mónica Martínez‐Gallo, José Bruno Montoro Ronsano, María Teresa Sanz Martínez, Roxana Paola Bury Macías
article en
1 citations

Abstract

Albuminemia and proteinuria affect rituximab t 1/2 and drug exposure in patients with glomerular diseases. Patients with proteinuria >2.4 g /24h may require higher frequent dosing for adequate rituximab exposure. Establishing an optimal dosing regimen in this population remains warranted.

Therapeutic Drug MonitoringVol. 47(6)
Universitat Autònoma de Barcelona (ES), Vall d'Hebron Institut de Recerca (ES), Vall d'Hebron Hospital Universitari (ES)
Good health and well-being
Openalex Percentile: Top 18%
Renal Diseases and Glomerulopathies
1.43
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