Gastrointestinal Complications of Systemic Sclerosis: A Case Report

Systemic sclerosis (SSc) is a rare, chronic systemic rheumatic disease. Gastrointestinal (GI) involvement is highly prevalent in SSc and any part of the GI tract may be affected. This can range from mild symptoms like heartburn and dysphagia to severe issues like abdominal distention, malnutrition, and fecal incontinence. In SSc patients, GI tract dysfunction significantly impacts the quality of life and is a major contributor to both morbidity and mortality. This case report highlights an 80-year-old female patient with SSc/CREST (Calcinosis, Raynaud's phenomenon, Esophageal dysfunction, Sclerodactyly, and Telangiectasia) syndrome experiencing severe GI involvement who presented to the emergency department with hypoxic respiratory failure and acute kidney injury. The patient and her family finally made the decision to transition to inpatient hospice care, focusing on comfort and dignity, leading to the patient's peaceful passing.

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Publication Details

Journal
Cureus
Published
2025-06-27
DOI
https://doi.org/10.7759/cureus.86844
Primary Topic
Systemic Sclerosis and Related Diseases
Type
article
Field-Weighted Citation Impact
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article

Gastrointestinal Complications of Systemic Sclerosis: A Case Report

Mohsen Arbabi, Prakash Patel, Saviz Saghari, Bella Garg
Cureus
Systemic Sclerosis and Related Diseases
article

Gastrointestinal Complications of Systemic Sclerosis: A Case Report

Mohsen Arbabi, Prakash Patel, Saviz Saghari, Bella Garg
article en

Abstract

Systemic sclerosis (SSc) is a rare, chronic systemic rheumatic disease. Gastrointestinal (GI) involvement is highly prevalent in SSc and any part of the GI tract may be affected. This can range from mild symptoms like heartburn and dysphagia to severe issues like abdominal distention, malnutrition, and fecal incontinence. In SSc patients, GI tract dysfunction significantly impacts the quality of life and is a major contributor to both morbidity and mortality. This case report highlights an 80-year-old female patient with SSc/CREST (Calcinosis, Raynaud's phenomenon, Esophageal dysfunction, Sclerodactyly, and Telangiectasia) syndrome experiencing severe GI involvement who presented to the emergency department with hypoxic respiratory failure and acute kidney injury. The patient and her family finally made the decision to transition to inpatient hospice care, focusing on comfort and dignity, leading to the patient's peaceful passing.

CureusVol. 17(6)
University of Kentucky (US), Anaheim University (US), Kaiser Permanente Anaheim Medical Center (US)
Good health and well-being
Openalex Percentile: Top 77%
Systemic Sclerosis and Related Diseases
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Gastrointestinal Complications of Systemic Sclerosis: A Case Report — Mohsen Arbabi, Prakash Patel, et al. · Cureus (2025) | TGRS Research Map | TGRS