The international, prospective CytOSorbⓇ treatMent Of critically ill patientS (COSMOS) registry: Interim results from the first 150 patients
The COSMOS registry highlights CS-associated improvements in lactate, creatinine, norepinephrine needs, fluid balance, and oxygenation. Mortality was favorable compared with risk-based predictions.Trial registration Clinicaltrials.gov Identifier: NCT05146336.
Authors
- Filippo Aucella (ORCID: https://orcid.org/0000-0003-1027-7049)
- Gabriella Bottari (ORCID: https://orcid.org/0000-0002-2723-9914)
- Bartosz Tyczynski
- Jorge Hidalgo (ORCID: https://orcid.org/0009-0005-2615-8150)
- Dietrich Henzler (ORCID: https://orcid.org/0000-0001-5511-6885)
- Julian Kreutz (ORCID: https://orcid.org/0000-0001-9498-9558)
- Joerg Scheier (ORCID: https://orcid.org/0000-0003-0520-3133)
- Ricard Ferrer (ORCID: https://orcid.org/0000-0002-4859-4747)
- Matthias Thielmann (ORCID: https://orcid.org/0000-0002-1007-2871)
- Aschraf El‐Essawi (ORCID: https://orcid.org/0000-0002-5583-039X)
- Andreas Baumann (ORCID: https://orcid.org/0000-0001-5907-7895)
- Jean–Louis Teboul (ORCID: https://orcid.org/0000-0002-5748-7820)
- Andreas Kribben (ORCID: https://orcid.org/0000-0003-4859-7507)
- Martin Bellgardt (ORCID: https://orcid.org/0000-0001-9447-0019)
- Efthymios Deliargyris (ORCID: https://orcid.org/0000-0002-1893-7024)
- Dana Tomescu (ORCID: https://orcid.org/0000-0001-9673-5754)
- Ulf Guenther (ORCID: https://orcid.org/0000-0003-4068-3849)
- Teresa Klaus (ORCID: https://orcid.org/0009-0005-5236-0969)
- Thomas Kirschning
- Thomas Günther Pomorski (ORCID: https://orcid.org/0000-0002-4889-0829)
- Fabio Silvio Taccone
- Weihong Fan
- Moritz Unglaube
Institutions
- Université Libre de Bruxelles (BE)
- Philipps University of Marburg (DE)
- Carol Davila University of Medicine and Pharmacy (RO)
- Université Paris-Saclay (FR)
- Casa Sollievo della Sofferenza (IT)
- Heart and Diabetes Center North Rhine-Westphalia (DE)
- Helios Dr. Horst Schmidt Kliniken Wiesbaden (DE)
- Central America Health Sciences University (BZ)
- Klinikum Oldenburg (DE)
- CytoSorbents (Germany) (DE)
- Essen University Hospital (DE)
- Bambino Gesù Children's Hospital (IT)
- Pius Hospital Oldenburg (DE)
- Vall d'Hebron Hospital Universitari (ES)
- Herford Hospital (DE)
- St. Josef-Hospital (DE)
- BG University Hospital Bergmannsheil Bochum (DE)
- CytoSorbents (United States) (US)
- Deutsches Herzzentrum München (DE)
- Institutul Clinic Fundeni (RO)
- West German Heart and Vascular Center Essen (DE)
- University of Duisburg-Essen (DE)
Publication Details
- Journal
- Journal of Intensive Medicine
- Published
- 2025-06-27
- DOI
- https://doi.org/10.1016/j.jointm.2025.05.001
- Citations
- 5
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 7.59