A unique case of gastrointestinal bleeding with splenomegaly

We present the case of a 61-year-old man with a 30-year history of iron-deficiency anemia and recurrent gastrointestinal bleeding, accompanied by splenomegaly and hypersplenism. Despite multiple endoscopy and imaging examinations, the source of bleeding remained elusive. The patient ultimately underwent exploratory laparotomy with splenectomy, which revealed a Meckel's diverticulum with stale hemorrhage, along with congestive changes in the spleen. Following surgery, the patient experienced a complete resolution of symptoms with normalization of hematological parameters. This case highlights Meckel's diverticulum as a rare cause of obscure gastrointestinal bleeding, with the unique presentation of splenomegaly due to extramedullary hematopoiesis.

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Publication Details

Journal
SAGE Open Medical Case Reports
Published
2025-06-27
DOI
https://doi.org/10.1177/2050313x251351454
Primary Topic
Gastrointestinal disorders and treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

A unique case of gastrointestinal bleeding with splenomegaly

Shihang Tang, Can Gan
SAGE Open Medical Case Reports
Gastrointestinal disorders and treatments
article

A unique case of gastrointestinal bleeding with splenomegaly

Shihang Tang, Can Gan
article en

Abstract

We present the case of a 61-year-old man with a 30-year history of iron-deficiency anemia and recurrent gastrointestinal bleeding, accompanied by splenomegaly and hypersplenism. Despite multiple endoscopy and imaging examinations, the source of bleeding remained elusive. The patient ultimately underwent exploratory laparotomy with splenectomy, which revealed a Meckel's diverticulum with stale hemorrhage, along with congestive changes in the spleen. Following surgery, the patient experienced a complete resolution of symptoms with normalization of hematological parameters. This case highlights Meckel's diverticulum as a rare cause of obscure gastrointestinal bleeding, with the unique presentation of splenomegaly due to extramedullary hematopoiesis.

SAGE Open Medical Case ReportsVol. 13
Chongqing University (CN), Sichuan University (CN), West China Hospital of Sichuan University (CN), Chongqing Cancer Hospital (CN)
Natural Science Foundation of Chongqing
Openalex Percentile: Top 74%
Gastrointestinal disorders and treatments
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A unique case of gastrointestinal bleeding with splenomegaly — Shihang Tang, Can Gan · SAGE Open Medical Case Reports (2025) | TGRS Research Map | TGRS