Inhalation of titanium dioxide nanoparticles during gestation alters placental bioenergetics in a sex-related manner in rats
These data show that there are sex-related mechanisms within the glycolytic pathway for increased glucose utilization. As increased metabolism of glucose by the placenta can reduce fetal glucose delivery, it may contribute to adverse effects on fetal growth induced by nano-TiO<sub>2</sub>.
Authors
- Andrew Menzies Gow
- Talia Seymore (ORCID: https://orcid.org/0000-0002-8969-9190)
- J J Herbert (ORCID: https://orcid.org/0000-0001-5676-2512)
- Changjiang Guo (ORCID: https://orcid.org/0000-0002-7447-3762)
- Alyssa Bellomo
- Phoebe A. Stapleton (ORCID: https://orcid.org/0000-0003-3049-4868)
- Debra L. Laskin (ORCID: https://orcid.org/0000-0003-1832-7311)
Institutions
- Environmental and Occupational Health Sciences Institute (US)
Publication Details
- Journal
- Placenta
- Published
- 2025-06-27
- DOI
- https://doi.org/10.1016/j.placenta.2025.06.018
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00