Menthol preferentially inhibits persistent Na+ current mediated by NaV1.8 in small-sized dural afferent neurons of rats

The results of this study suggest that menthol exerts an analgesic effect by preferentially inhibiting persistent TTX-R I Na and modulating the inactivation and recovery kinetics of TTX-R Na + channels.

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Publication Details

Journal
Neuroreport
Published
2025-06-24
DOI
https://doi.org/10.1097/wnr.0000000000002189
Citations
1
Primary Topic
Ion Channels and Receptors
Type
article
Field-Weighted Citation Impact
1.46
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article

Menthol preferentially inhibits persistent Na+ current mediated by NaV1.8 in small-sized dural afferent neurons of rats

Il‐Sung Jang, Michiko Nakamura
1 citations
Neuroreport
Ion Channels and Receptors
1.46
article

Menthol preferentially inhibits persistent Na+ current mediated by NaV1.8 in small-sized dural afferent neurons of rats

Il‐Sung Jang, Michiko Nakamura
article en
1 citations

Abstract

The results of this study suggest that menthol exerts an analgesic effect by preferentially inhibiting persistent TTX-R I Na and modulating the inactivation and recovery kinetics of TTX-R Na + channels.

NeuroreportVol. 36(12)
Kyungpook National University (KR)
Openalex Percentile: Top 20%
Ion Channels and Receptors
1.46
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Menthol preferentially inhibits persistent Na+ current mediated by NaV1.8 in small-sized dural afferent neurons of rats — Il‐Sung Jang, Michiko Nakamura · Neuroreport (2025) | TGRS Research Map | TGRS