Progress of the Molecular Mechanism of Genistein against Colorectal Cancer

As a highly prevalent malignant tumor worldwide, the development of therapeutic agents for colorectal cancer has been a hot spot of medical research. Genistein, as a natural isoflavone compound, has attracted much attention in recent years for its remarkable anti-tumor activity. Studies have shown that genistein can regulate the proliferation, apoptosis and metastasis of colorectal cancer cells through multi-targets and multi-pathways, demonstrating a unique molecular mechanism of action. In-depth analysis of the molecular mechanism of genistein against colorectal cancer will not only help to elucidate the material basis of its efficacy, but also provide a theoretical basis for the design of new targeted drugs, which is of great scientific value and clinical translation significance.

Publication Details

Journal
MEDS Clinical Medicine
Published
2025-01-01
DOI
https://doi.org/10.23977/medsc.2025.060303
Primary Topic
Phytoestrogen effects and research
Type
article
Field-Weighted Citation Impact
0.00
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article

Progress of the Molecular Mechanism of Genistein against Colorectal Cancer

MEDS Clinical Medicine
Phytoestrogen effects and research
article

Progress of the Molecular Mechanism of Genistein against Colorectal Cancer

article en

Abstract

As a highly prevalent malignant tumor worldwide, the development of therapeutic agents for colorectal cancer has been a hot spot of medical research. Genistein, as a natural isoflavone compound, has attracted much attention in recent years for its remarkable anti-tumor activity. Studies have shown that genistein can regulate the proliferation, apoptosis and metastasis of colorectal cancer cells through multi-targets and multi-pathways, demonstrating a unique molecular mechanism of action. In-depth analysis of the molecular mechanism of genistein against colorectal cancer will not only help to elucidate the material basis of its efficacy, but also provide a theoretical basis for the design of new targeted drugs, which is of great scientific value and clinical translation significance.

MEDS Clinical MedicineVol. 6(3)
Good health and well-being
Openalex Percentile: Top 77%
Phytoestrogen effects and research
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