Common Neural Deficits in Social and Monetary Reinforcement Learning in Schizophrenia
Overall, the findings indicate that although SZ appear to have intact brain activation when receiving feedback about their choices, they may struggle to recruit the necessary circuitry in regions associated with generating expected values to successfully modulate their choices based on the received feedback. This aligns with literature on monetary RL in SZ and suggests that activation patterns may be similar during social RL.
Authors
- Jay Nierenberg (ORCID: https://orcid.org/0000-0002-4643-1020)
- Deanna M. Barch (ORCID: https://orcid.org/0000-0003-1693-8506)
- Jaisal Merchant (ORCID: https://orcid.org/0000-0002-9644-9915)
- Matthew J. Hoptman (ORCID: https://orcid.org/0000-0003-4485-6102)
- Julia A Ermel
- Erin K. Moran (ORCID: https://orcid.org/0000-0002-7813-8099)
- Pamela D. Butler (ORCID: https://orcid.org/0000-0003-4346-9944)
Institutions
- Nathan Kline Institute for Psychiatric Research (US)
- Washington University in St. Louis (US)
- New York University (US)
Publication Details
- Journal
- Schizophrenia Bulletin
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1093/schbul/sbaf097
- Primary Topic
- Neural and Behavioral Psychology Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute of Mental Health