Cholelithiasis Rates In Kidney Transplantation and Long-term Complications and – 14 Years of Experience In Tertiary Hospital

Objectives: The increase in the number of kidney transplants and the prolongation of kidney transplantation duration enhance the complications of kidney transplantation. Within the scope of this research, we aimed to elucidate kidney transplantation complications (cardiac, hepatobiliary, opportunistic infections, avascular necrosis, NODAT) in kidney transplant recipient patients followed in our institution. Method: A total of 300 patients who underwent renal transplantation in our healthcare facility have been evaluated in this retrospective analysis. The sociodemographic properties of age, sex, graft type, pre-transplant dialysis status, and KFRT etiologies were obtained from hospital records. Avascular necrosis, malignity, cardiac deficiency, or development of coronary arterial disorder, NODAT, opportunistic infections, and hepatobiliary complications have been evaluated. Results: The NODAT development rate in renal transplant patients was 17.5% in the case of live donors and 28.6% in cadaveric transplants (p=0.07). Again, 34% of the patients had biliary or liver disorders such as cholelithiasis in the follow-ups, which was significantly higher in the transplants from cadavers with regard to graft type (p=0.009). Cytomegalovirus infection was observed in 50 patients, and BK virus infection in 36 patients. The rate of CMV infection was significantly higher in the first year after kidney transplantation. At the same time, BK was found to be considerably higher in the first two years (p<0.05). Conclusion: This study elaborated on the complication rate and compiled the risk factors of renal transplant patients. It is original about post-transplant cholelithiasis development and incidence data, in addition to pointing out hepatobiliary complications