C–H functionalisation of [2.2]paracyclophane under copper catalysis
The direct C-H functionalisation of [2.2]paracyclophane (PCP) by forging diverse C-C bonds is appealing, yet has remained underexplored. Herein, we describe a copper-catalysed non-directed C-H arylation and alkenylation of PCP with various iodonium salts. This method features high selectivity, broad substrate scope, and mild conditions, constituting a practical platform for modular access to PCP derivatives.
Authors
- Kai Liu (ORCID: https://orcid.org/0000-0002-0012-798X)
- Dan‐Qian Xu (ORCID: https://orcid.org/0000-0003-0152-0860)
- Xin Yang (ORCID: https://orcid.org/0000-0003-1041-0030)
- Shao‐Jie Lou (ORCID: https://orcid.org/0000-0003-3700-6812)
- Jun Pu (ORCID: https://orcid.org/0009-0001-8580-7086)
- Yue Wang (ORCID: https://orcid.org/0000-0001-6936-5081)
- Kun Zhou (ORCID: https://orcid.org/0000-0003-0502-2623)
- Ruirui Wu
- Xin-Rou Zhong
Institutions
- Zhejiang University of Technology (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc02283e
- Citations
- 1
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.94