The Anti-Osteoporosis Effects of Panax japonicus via Downregulation of Inflammatory Factors: A Network Pharmacology and Ovariectomized Rat Model Study
<i>Panax japonicus</i> was found to contain 52 compounds and 65 targets in the treatment of osteoporosis. The administration of <i>Panax japonicus</i> could mitigate osteoporosis in rats induced by ovariectomy, and one of the mechanisms was associated with downregulating the expression of inflammatory factors.
Authors
- Xinbo Shi
- Yumiao Zhang (ORCID: https://orcid.org/0000-0002-6166-0470)
- Yingang Li
- Yuchen Zhang (ORCID: https://orcid.org/0000-0003-3378-1520)
- Pan Y (ORCID: https://orcid.org/0000-0002-3579-4395)
- Yang Liu (ORCID: https://orcid.org/0000-0003-2626-375X)
Institutions
- Xidian University (CN)
- Affiliated Hospital of Shaanxi University of Chinese Medicine (CN)
- China XD Group (China) (CN)
- Xijing Hospital (CN)
- Shaanxi University of Chinese Medicine (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Endocrine Metabolic & Immune Disorders - Drug Targets
- Published
- 2025-06-20
- DOI
- https://doi.org/10.2174/0118715303371787250609162705
- Citations
- 2
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.61