New Baitouweng Decoction alleviated DSS-induced colitis through the FXR/NLRP3 signaling pathway by regulating gut microbiota and bile acids
NBD had a therapeutic effect on DSS-induced UC in a mouse model by regulating the gut microbiota, BAs, and subsequent FXR-NLRP3 pathway for decreasing the release of pro-inflammatory factors and repairing the intestinal barrier to preserve the equilibrium.
Authors
- Zhao-Wei Shan (ORCID: https://orcid.org/0000-0002-5644-8010)
- Yi Xu (ORCID: https://orcid.org/0000-0002-6917-184X)
- Bu Shu
- Zhiwei Miao (ORCID: https://orcid.org/0000-0003-2540-5517)
- Liu Li (ORCID: https://orcid.org/0000-0002-4898-3013)
- Yingjie Wei (ORCID: https://orcid.org/0000-0003-4338-1336)
- Xin Gu (ORCID: https://orcid.org/0000-0002-8040-7366)
Institutions
- Nanjing University of Chinese Medicine (CN)
Publication Details
- Journal
- Gastroenterology report
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/gastro/goaf055
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Government of Jiangsu Province
- China Academy of Chinese Medical Sciences