Ovarian hyperstimulation revealing a functional gonadotroph adenoma: a case report

We report the case of a functional gonadotropic adenoma (FGA) in a 32-year-old woman, initially revealed by ovarian hyperstimulation. Hormonal investigations strongly suggested an FGA; pelvic ultrasound revealed macrofollicular ovarian enlargement. Despite a clear clinical picture, diagnosis was delayed until the appearance of cranial tumor syndrome with ophthalmological impairment and pituitary dysfunction. The ophthalmological emergency necessitated urgent surgery, allowing both decompression of the optic pathways and a reduction in hyperestrogenism. Despite their rarity, it is essential to recognize FGA to avoid potentially fatal complications.

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Publication Details

Journal
Pan African Medical Journal
Published
2025-01-01
DOI
https://doi.org/10.11604/pamj.2025.51.57.47982
Primary Topic
Reproductive Biology and Fertility
Type
article
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Ovarian hyperstimulation revealing a functional gonadotroph adenoma: a case report

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Ovarian hyperstimulation revealing a functional gonadotroph adenoma: a case report

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article en

Abstract

We report the case of a functional gonadotropic adenoma (FGA) in a 32-year-old woman, initially revealed by ovarian hyperstimulation. Hormonal investigations strongly suggested an FGA; pelvic ultrasound revealed macrofollicular ovarian enlargement. Despite a clear clinical picture, diagnosis was delayed until the appearance of cranial tumor syndrome with ophthalmological impairment and pituitary dysfunction. The ophthalmological emergency necessitated urgent surgery, allowing both decompression of the optic pathways and a reduction in hyperestrogenism. Despite their rarity, it is essential to recognize FGA to avoid potentially fatal complications.

Pan African Medical JournalVol. 51
University of Algiers Benyoucef Benkhedda (DZ), Centre Hospitalo-Universitaire Bab El Oued (DZ)
Zero hunger
Openalex Percentile: Top 79%
Reproductive Biology and Fertility
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