Analysis of risk factors for anastomotic leakage in patients after surgical treatment of colorectal cancer: a systematic literature review

This systematic literature review analyzes the risk factors for anastomotic leakage (AL) in the surgical treatment of colorectal cancer. Based on 42 studies, key risk predictors for AL were identified. The incidence of AL in the studies included in this review ranged from 2,8% to 24,7%. The introduction of the RALAR scale significantly improved the objective assessment of AL risk. A comprehensive approach to prevention, based on risk stratification and treatment personalization, can significantly improve the outcomes of surgical treatment for colorectal cancer.