Detection of malignant liver tumors and intrahepatic bile ducts in the Republic of Sakha (Yakutia)

The article presents a cross-sectional retrospective study of cases of malignant neoplasms (MN) of the liver and intrahepatic bile ducts (C22) in the Republic of Sakha (Yakutia) (RS (Y) for 2010–2019 based on statistical registration forms No. 7 and 35. During the study period, significantly increased levels of morbidity and mortality from malignant neoplasms of the liver and intrahepatic bile ducts were recorded. At the same time, the proportion of detection of the studied pathology at early stages remains low, despite the strengthening of diagnostic measures within the framework of preventive examinations and screening programs. In the dynamics for 2015–2019 in the RS (Y), the proportion of patients with MN of the liver and intrahepatic bile ducts who were under observation for 5 years decreased, while the contingent of patients with this pathology increased. The obtained data substantiate the need to improve organizational approaches to early diagnosis and treatment, optimize patient routing, and study pre-cancerous factors of liver cancer in residents of the Republic of Sakha (Yakutia).