Life Table Evaluation of Synthetic and Botanical Insecticides on Drosophila melanogaster: Comparative Effects of Chlorpyrifos, Cypermethrin, and Azadirachta indica Leaf Extract

The effects of chlorpyrifos, cypermethrin, and Azadirachta indica leaf extract on Drosophila melanogaster have been quantified in the present study “Life Table Evaluation of Synthetic and Botanical Insecticides on Drosophila melanogaster: Comparative Effects of Chlorpyrifos, Cypermethrin, and Azadirachta indica leaf extract,” which also provides insightful information of their impact on the life stages and mortality rates of this model organism. This study demonstrated that Drosophila undergoes age-specific mortality, with mortality rates frequently rising in later stages of their development. Drosophila were subjected to varying doses of cypermethrin, chlorpyrifos, and neem leaf extract for 2 hours. They were then transferred to a fresh medium and reared for a generation. The various life table parameters were analysed and quantified. The research demonstrated that Azadirachta indica leaf extract emerged as a promising replacement for synthetic pesticides like cypermethrin and chlorpyrifos, especially at higher dosages. The research also exhibited a clear dose-dependent effect, with larger dosages of cypermethrin, chlorpyrifos, and neem leaf extract resulting in pronounced reductions in Drosophila survival. This shows how important it is to carefully assess pesticide dose and choice when employing them in agricultural approaches to reduce the influence on organisms that are not intended targets.