THE THIA-MICHAEL ADDITION REACTION: A SIMPLE AND EASY GREEN ONE-POT SYNTHESIS OF BIS 1,2,3- TRIAZOLYL β-MERCAPTO CARBONYL SPIN-OFFS

The present investigation deals with an efficient synthesis of a library of bis β-mercapto carbonyl triazole derivatives via a one-pot three-component solvent-free green protocol. Significance of the protocol has been realized due to its mild reaction conditions, cost effectiveness, quantitative yield of the product within a short reaction time, easy workup, and eco-friendliness. Water as the green solvent facilitates easy separation of pure products from the reaction medium without the need for chromatographic separation.