Ovarian steroid cell tumor “not otherwise specified” in a reproductive-aged female presenting with abnormal uterine bleeding and virilization: A case report

Steroid cell tumors occur in <0.1% of all ovarian tumors, and steroid cell tumors, not otherwise specified occur in 80% of those steroid cell tumor cases. In the Philippines, there is only one published case of a steroid cell tumor, not otherwise specified. This is a case of a 25-year-old nulligravid, who manifested with heavy menstrual bleeding accompanied by hirsutism, and deepening of the voice. Ultrasound revealed the left ovary with a well-circumscribed, hypoechoic solid mass, measuring 36.8 mm × 34 mm × 32.1 mm with benign features on the International Ovarian Tumor Analysis. The patient underwent a left salpingo-oophorectomy with frozen section. Final histopathology showed a steroid cell tumor, not otherwise specified. Prompt surveillance and increasing awareness of steroid cell tumors, especially those that manifest with abnormal uterine bleeding and virilization, may initiate prompt and proper management that can have an impact on the quality of life of the patient.

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Publication Details

Journal
Philippine Journal of Obstetrics and Gynecology
Published
2025-04-01
DOI
https://doi.org/10.4103/pjog.pjog_33_24
Primary Topic
Ovarian function and disorders
Type
article
Field-Weighted Citation Impact
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article

Ovarian steroid cell tumor “not otherwise specified” in a reproductive-aged female presenting with abnormal uterine bleeding and virilization: A case report

Maria Mikaela Vitug Comendador, Jay Arnold Famador
Philippine Journal of Obstetrics and Gynecology
Ovarian function and disorders
article

Ovarian steroid cell tumor “not otherwise specified” in a reproductive-aged female presenting with abnormal uterine bleeding and virilization: A case report

Maria Mikaela Vitug Comendador, Jay Arnold Famador
article en

Abstract

Steroid cell tumors occur in <0.1% of all ovarian tumors, and steroid cell tumors, not otherwise specified occur in 80% of those steroid cell tumor cases. In the Philippines, there is only one published case of a steroid cell tumor, not otherwise specified. This is a case of a 25-year-old nulligravid, who manifested with heavy menstrual bleeding accompanied by hirsutism, and deepening of the voice. Ultrasound revealed the left ovary with a well-circumscribed, hypoechoic solid mass, measuring 36.8 mm × 34 mm × 32.1 mm with benign features on the International Ovarian Tumor Analysis. The patient underwent a left salpingo-oophorectomy with frozen section. Final histopathology showed a steroid cell tumor, not otherwise specified. Prompt surveillance and increasing awareness of steroid cell tumors, especially those that manifest with abnormal uterine bleeding and virilization, may initiate prompt and proper management that can have an impact on the quality of life of the patient.

Philippine Journal of Obstetrics and GynecologyVol. 49(2)
Makati Medical Center (PH)
Openalex Percentile: Top 79%
Ovarian function and disorders
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