Long-Term Survival Following Multimodal Therapy with Sunitinib and Surgery for Recurrent Duodenal Gastrointestinal Stromal Tumor

This case highlights the potential of combining sunitinib with surgery to manage drug-resistant GIST. Localized surgical resection of resistant lesions, integrated with systemic therapy, may offer prolonged survival in selected patients. Further studies are needed to define the optimal role of surgery in this context.

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Publication Details

Journal
Surgical Case Reports
Published
2025-01-01
DOI
https://doi.org/10.70352/scrj.cr.25-0260
Primary Topic
Gastrointestinal Tumor Research and Treatment
Type
article
Field-Weighted Citation Impact
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article

Long-Term Survival Following Multimodal Therapy with Sunitinib and Surgery for Recurrent Duodenal Gastrointestinal Stromal Tumor

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Surgical Case Reports
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Long-Term Survival Following Multimodal Therapy with Sunitinib and Surgery for Recurrent Duodenal Gastrointestinal Stromal Tumor

Kotaro Yamashita, Yuichiro Doki, Eiichi Mori, Koji Tanaka, Tomomi Fujii, Kiyokazu Nakajima, Tomoki Makino, Takuro Saito, Hidetoshi Eguchi, Manatsu Mizuno, Takaomi Hagi, Yoshito Tomimaru, Yukinori Kurokawa, Tsuyoshi Takahashi, Kota Momose
article en

Abstract

This case highlights the potential of combining sunitinib with surgery to manage drug-resistant GIST. Localized surgical resection of resistant lesions, integrated with systemic therapy, may offer prolonged survival in selected patients. Further studies are needed to define the optimal role of surgery in this context.

Surgical Case ReportsVol. 11(1)
The University of Osaka (JP)
Zero hunger
Openalex Percentile: Top 77%
Gastrointestinal Tumor Research and Treatment
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