Comparative efficacy of adjuvant FOLFOX vs. FLOT following neoadjuvant FLOT in patients with locally advanced gastric cancer
Among patients undergoing surgery after neoadjuvant FLOT, adjuvant FOLFOX showed comparable efficacy to FLOT, suggesting its potential as an alternative option, particularly for patients with deteriorated ECOG PS or those who developed chemotherapy intolerance postoperatively. These findings inform treatment strategies and optimize adjuvant therapy selection based on individual patient profiles.
Authors
- Hayriye Tatlı Doğan (ORCID: https://orcid.org/0000-0003-4318-2775)
- Furkan Ceylan (ORCID: https://orcid.org/0000-0002-1944-0861)
- Burak Bi̇lgi̇n (ORCID: https://orcid.org/0000-0003-1717-8246)
- Safa Can Efil (ORCID: https://orcid.org/0000-0001-9586-2858)
- Eren Göktuğ Ceylan (ORCID: https://orcid.org/0009-0003-1244-4530)
- Şebnem Yücel (ORCID: https://orcid.org/0000-0001-6235-7927)
- Doğan Uncu (ORCID: https://orcid.org/0000-0002-0929-3271)
- Didem Şener Dede (ORCID: https://orcid.org/0000-0002-9756-5942)
- Serhat Sekmek (ORCID: https://orcid.org/0000-0003-4650-248X)
- Mehmet Alı Nahıt Şendur (ORCID: https://orcid.org/0000-0001-7021-6139)
- Muhammed Bülent Akıncı (ORCID: https://orcid.org/0000-0001-7575-9925)
- Ateş Kutay Tenekeci (ORCID: https://orcid.org/0009-0007-6224-945X)
- Bülent Yalçın (ORCID: https://orcid.org/0000-0002-4431-8948)
- Mehmet Çakmak (ORCID: https://orcid.org/0000-0002-5362-6109)
Institutions
- Hacettepe University (TR)
Publication Details
- Journal
- TURKISH JOURNAL OF MEDICAL SCIENCES
- Published
- 2025-06-20
- DOI
- https://doi.org/10.55730/1300-0144.6002
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00