The Practice and Exploration of Online-Offline Blended Teaching in the <i>Biostatistics</i> Course

充分结合线上和线下教学优势的线上线下混合式教学已经成为当前教育教学改革的热点。本论文详细阐述了《生物统计学》课程的线上线下混合式教学的实施方案，并选取了重庆邮电大学生物信息专业2020级的81例本科生为线上教学组，2021级的76例本科生为线下教学组，2022级的76例本科生为混合教学组(线上线下混合式教学组)，比较各组的期末理论考试成绩和学期总评成绩。结果表明混合教学组在期末考试的平均分、高分段以及总评成绩的优良率方面都显著优于线上教学组和线下教学组。因此，优化整合《生物统计学》的混合式教学资源，深化课程教学内容，创新线上线下混合式教学模式，可以有效地提高《生物统计学》课程的教学质量。Online-offline blended teaching, which fully integrates the advantages of both instructional modalities, has become a focal point in current educational reform. This paper elaborates on the implementation plan of online-offline blended teaching for the Biostatistics course. A comparative study was conducted using 81 undergraduate students from the 2020 cohort majoring in Bioinformatics at Chongqing University of Posts and Telecommunications as the online teaching group, 76 students from the 2021 cohort as the offline teaching group, and 76 students from the 2022 cohort as the blended teaching group (online-offline blended teaching group). The final theoretical exam scores and overall course evaluations were compared across groups. Results indicated that the blended teaching group significantly outperformed both the online and offline groups in terms of average exam scores, high-score segments, and the excellent/good rate in overall evaluations. Therefore, optimizing blended teaching resources for Biostatistics, deepening curricular content, and innovating blended teaching models can effectively enhance the instructional quality of the Biostatistics course.