Unsupervised machine learning revealed a correlation between low-dose statins and favorable outcomes in ICH patients

Unsupervised machine learning revealed a correlation between low-dose statins and patient prognosis. Subsequent analyses and validation indicated that for patients with intracerebral hemorrhage (ICH) in the cerebral hemisphere, early administration of low-dose hydrophilic statins is associated with reduced mortality, and statins are associated with a reduced rate of ischemic stroke occurrence. For all ICH patients, low-dose statins are associated with a lower rate of unfavorable functional outcomes but show no significant association with hematoma expansion.

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Publication Details

Journal
Frontiers in Neurology
Published
2025-06-24
DOI
https://doi.org/10.3389/fneur.2025.1573036
Citations
3
Primary Topic
Intracerebral and Subarachnoid Hemorrhage Research
Type
article
Field-Weighted Citation Impact
4.17

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article

Unsupervised machine learning revealed a correlation between low-dose statins and favorable outcomes in ICH patients

Chaohua Cui, Hong Guan, Yuru Liang, Tonghua Long
3 citations
Frontiers in Neurology
Intracerebral and Subarachnoid Hemorrhage Research
4.17
article

Unsupervised machine learning revealed a correlation between low-dose statins and favorable outcomes in ICH patients

Chaohua Cui, Hong Guan, Yuru Liang, Tonghua Long
article en
3 citations

Abstract

Unsupervised machine learning revealed a correlation between low-dose statins and patient prognosis. Subsequent analyses and validation indicated that for patients with intracerebral hemorrhage (ICH) in the cerebral hemisphere, early administration of low-dose hydrophilic statins is associated with reduced mortality, and statins are associated with a reduced rate of ischemic stroke occurrence. For all ICH patients, low-dose statins are associated with a lower rate of unfavorable functional outcomes but show no significant association with hematoma expansion.

Frontiers in NeurologyVol. 16
Affiliated Hospital of Youjiang Medical University for Nationalities (CN)
Specific Research Project of Guangxi for Research Bases and Talents
Good health and well-being
Openalex Percentile: Top 6%
Intracerebral and Subarachnoid Hemorrhage Research
4.17
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