Unsupervised machine learning revealed a correlation between low-dose statins and favorable outcomes in ICH patients
Unsupervised machine learning revealed a correlation between low-dose statins and patient prognosis. Subsequent analyses and validation indicated that for patients with intracerebral hemorrhage (ICH) in the cerebral hemisphere, early administration of low-dose hydrophilic statins is associated with reduced mortality, and statins are associated with a reduced rate of ischemic stroke occurrence. For all ICH patients, low-dose statins are associated with a lower rate of unfavorable functional outcomes but show no significant association with hematoma expansion.
Authors
- Chaohua Cui (ORCID: https://orcid.org/0000-0002-9519-5757)
- Hong Guan (ORCID: https://orcid.org/0000-0001-5053-5052)
- Yuru Liang (ORCID: https://orcid.org/0000-0003-3517-8223)
- Tonghua Long
Institutions
- Affiliated Hospital of Youjiang Medical University for Nationalities (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-06-24
- DOI
- https://doi.org/10.3389/fneur.2025.1573036
- Citations
- 3
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 4.17
Funders
- Specific Research Project of Guangxi for Research Bases and Talents