Electrocardiographic and Echocardiographic Assessment in Patients with Chronic Obstructive Pulmonary Disease

Background: Chronic Obstructive Pulmonary Disease (COPD) significantly affects both respiratory and cardiovascular systems.Cardiac dysfunctions-often undiagnosed-contribute substantially to morbidity in COPD patients.To evaluate the prevalence and pattern of electrocardiographic (ECG) and echocardiographic abnormalities in COPD patients, and their correlation with disease severity.Methods: A cross-sectional observational study was conducted on 250 spirometry-confirmed COPD patients across all severity stages.Standard 12-lead ECG and echocardiographic evaluations were performed.ECG assessed arrhythmias, conduction abnormalities, and QTc prolongation, while echocardiography examined right ventricular (RV) hypertrophy and pulmonary artery hypertension (PAH).Statistical analyses included chi-square tests and multivariate regression.Results: Out of 250 patients (mean age 60.4 years; 60% female), ECG abnormalities were noted in 25% (arrhythmia), 18% (conduction defects), and 10% (QTc prolongation).Echocardiography revealed RV hypertrophy in 30% and PAH in 23%.A significant association existed between COPD severity and cardiac abnormalities.For instance, RV hypertrophy rose from 5% in mild to 68% in very severe cases (p=0.02); and PAH from 4% to 67% (p=0.01).Regression analysis identified reduced FEV1/FVC ratio, hypertension, and diabetes mellitus as independent predictors of RV hypertrophy and arrhythmia.Conclusion: Cardiac dysfunction increases with COPD severity.Routine ECG and echocardiographic screening should be integrated into COPD management to detect early cardiovascular complications and guide timely interventions.

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Publication Details

Journal
SSR Institute of International Journal of Life Sciences
Published
2025-05-01
DOI
https://doi.org/10.21276/ssr-iijls.2025.11.3.48
Primary Topic
Pulmonary Hypertension Research and Treatments
Type
article
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article

Electrocardiographic and Echocardiographic Assessment in Patients with Chronic Obstructive Pulmonary Disease

Sushant Swaroop Das, Satadru K. Lahiri, Ishita Das, Santanu Das et al.
SSR Institute of International Journal of Life Sciences
Pulmonary Hypertension Research and Treatments
article

Electrocardiographic and Echocardiographic Assessment in Patients with Chronic Obstructive Pulmonary Disease

Sushant Swaroop Das, Satadru K. Lahiri, Ishita Das, Santanu Das, Bipasha Adhvaryu
article en

Abstract

Background: Chronic Obstructive Pulmonary Disease (COPD) significantly affects both respiratory and cardiovascular systems.Cardiac dysfunctions-often undiagnosed-contribute substantially to morbidity in COPD patients.To evaluate the prevalence and pattern of electrocardiographic (ECG) and echocardiographic abnormalities in COPD patients, and their correlation with disease severity.Methods: A cross-sectional observational study was conducted on 250 spirometry-confirmed COPD patients across all severity stages.Standard 12-lead ECG and echocardiographic evaluations were performed.ECG assessed arrhythmias, conduction abnormalities, and QTc prolongation, while echocardiography examined right ventricular (RV) hypertrophy and pulmonary artery hypertension (PAH).Statistical analyses included chi-square tests and multivariate regression.Results: Out of 250 patients (mean age 60.4 years; 60% female), ECG abnormalities were noted in 25% (arrhythmia), 18% (conduction defects), and 10% (QTc prolongation).Echocardiography revealed RV hypertrophy in 30% and PAH in 23%.A significant association existed between COPD severity and cardiac abnormalities.For instance, RV hypertrophy rose from 5% in mild to 68% in very severe cases (p=0.02); and PAH from 4% to 67% (p=0.01).Regression analysis identified reduced FEV1/FVC ratio, hypertension, and diabetes mellitus as independent predictors of RV hypertrophy and arrhythmia.Conclusion: Cardiac dysfunction increases with COPD severity.Routine ECG and echocardiographic screening should be integrated into COPD management to detect early cardiovascular complications and guide timely interventions.

SSR Institute of International Journal of Life SciencesVol. 11(3)
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Pulmonary Hypertension Research and Treatments
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Electrocardiographic and Echocardiographic Assessment in Patients with Chronic Obstructive Pulmonary Disease — Sushant Swaroop Das, Satadru K. Lahiri, et al. · SSR Institute of International Journal of Life Sciences (2025) | TGRS Research Map | TGRS