A case of extensive Fournier’s gangrene induced by dual infection with multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa

Fournier's gangrene is a rare urological condition with a poor prognosis and an extremely high mortality rate. Infections caused by pathogenic microorganisms play a critical role in the pathogenesis of Fournier's gangrene. Rapid assessment and thorough debridement are crucial for survival and prognosis of patients with this disease. The present case involved a 62-year-old male patient with poorly controlled diabetes, who presented with unexplained scrotal swelling for 2 days at a local hospital where scrotal surgical debridement was performed. However, the procedure was unsuccessful. This case was characterized by rapid disease progression, widespread wound involvement, and dual infection with multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa . Our team performed early, extensive surgical debridement and, based on the results of antimicrobial susceptibility testing, initiated combination antibiotic therapy. The patient's condition improved significantly after these interventions. However, the treatment was ultimately discontinued by the patient's family for personal reasons, and follow-up care was declined.

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Publication Details

Journal
Chinese Journal of Plastic and Reconstructive Surgery
Published
2025-06-24
DOI
https://doi.org/10.1016/j.cjprs.2025.06.005
Primary Topic
Streptococcal Infections and Treatments
Type
article
Field-Weighted Citation Impact
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article

A case of extensive Fournier’s gangrene induced by dual infection with multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa

Yuan You, Feng Long, Zairong Wei, Yang Jian et al.
1 links
Chinese Journal of Plastic and Reconstructive Surgery
Streptococcal Infections and Treatments
article

A case of extensive Fournier’s gangrene induced by dual infection with multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa

Yuan You, Feng Long, Zairong Wei, Yang Jian, Shun-Cai Gao, X. Pan
article en

Abstract

Fournier's gangrene is a rare urological condition with a poor prognosis and an extremely high mortality rate. Infections caused by pathogenic microorganisms play a critical role in the pathogenesis of Fournier's gangrene. Rapid assessment and thorough debridement are crucial for survival and prognosis of patients with this disease. The present case involved a 62-year-old male patient with poorly controlled diabetes, who presented with unexplained scrotal swelling for 2 days at a local hospital where scrotal surgical debridement was performed. However, the procedure was unsuccessful. This case was characterized by rapid disease progression, widespread wound involvement, and dual infection with multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa . Our team performed early, extensive surgical debridement and, based on the results of antimicrobial susceptibility testing, initiated combination antibiotic therapy. The patient's condition improved significantly after these interventions. However, the treatment was ultimately discontinued by the patient's family for personal reasons, and follow-up care was declined.

Chinese Journal of Plastic and Reconstructive SurgeryVol. 7(4)
Zunyi Medical University (CN), Affiliated Hospital of Zunyi Medical College (CN)
Openalex Percentile: Top 79%
Streptococcal Infections and Treatments
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