Prevalence of Hepatitis B Virus Infection among Pregnant Women at the Koulikoro District Health Center

The objective of this study was to assess the prevalence of HBsAg among pregnant women in the Gynecology and Obstetrics Department. It was a descriptive and analytical cross-sectional study conducted from May 2019 to April 2020 in the Gynecology and Obstetrics Department of the Koulikoro District Health Center. Results: During this period, we screened 424 pregnant women for HBsAg. Among them, 68 tested positive, giving a prevalence rate of 16%. The average age of the participants was 26 ± 5 years, with extremes ranging from 15 to 37 years. About 35.3% of the women were pauciparous. Approximately 67.6% had their first prenatal consultation in the second trimester. Among them, 7.4% had a family history of liver disease. Risk factors associated with HBsAg carriage included female genital cutting, blood transfusion, and tattooing/scarification. Hepatic cytolysis was found in 19.1% of cases; viral replication was observed in 29.4%, and high viral load in 20.6%. The most common infection pattern was HBeAg-negative chronic hepatitis B. Serovaccination was absent in 7.4% of the newborns.