Interaction of Some Flavonoids Analogs with Sphingosine Kinase-1 as a Therapeutic Alternative to Treat Cancer
Reports are indicating that some biomolecules can regulate cancer development. In this way, some data suggest that sphingosine kinases (SphK1 and SphK2) can decrease cancer cell growth through the activation of different biomolecules. It is noteworthy that several SphK1 blockers have been used to treat decreased cancer cell growth; however, their interaction with SphK1 is unclear. Therefore, the aim of this investigation was to determine the possible coupling of some flavonoid analogs (1-19) wit
Authors
- Bargallo-Rocha Juan Enrique
- Rosas‐Nexticapa Marcela (ORCID: https://orcid.org/0000-0001-7119-4728)
- Magdalena Alvarez-Ramirez (ORCID: https://orcid.org/0000-0003-0046-4342)
- Cauich-Carrillo Regina (ORCID: https://orcid.org/0000-0002-7166-5048)
- Lauro Figueroa-Valverde (ORCID: https://orcid.org/0000-0001-6801-6402)
- Melgarejo-Gutierrez Montserrat Alheli
- Garcimarrero-Espino Alejandra Eli
Institutions
- Autonomous University of Campeche (MX)
Publication Details
- Journal
- Clinical Cancer Investigation Journal
- Published
- 2025-01-01
- DOI
- https://doi.org/10.51847/tljedpf9ku
- Primary Topic
- Sphingolipid Metabolism and Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00