Multiscale computational insights into 5-fluorouracil delivery <i>via</i> zeolite imidazole frameworks (ZIFs)
Using a multiscale computational approach, the adsorption of 5-FU in ZIF-8 and a modified ZIF was studied. The modified ZIF showed higher binding affinity and loading capacity, highlighting its superior performance for drug delivery applications.
Authors
- George E. Froudakis (ORCID: https://orcid.org/0000-0002-6907-1822)
- Emmanuel Klontzas (ORCID: https://orcid.org/0000-0002-1974-5198)
- Emmanuel Tyllianakis
- Giorgio Turtú
- Marco Severi (ORCID: https://orcid.org/0000-0001-9133-939X)
- Francesco Zerbetto (ORCID: https://orcid.org/0000-0002-2419-057X)
- Michail Vlachos
Institutions
- University of Crete (GR)
- National Hellenic Research Foundation (GR)
- University of Bologna (IT)
Publication Details
- Journal
- RSC Pharmaceutics
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5pm00058k
- Primary Topic
- Metal-Organic Frameworks: Synthesis and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Crete
- Università di Bologna