Research Progress in Evaluating CTD-ILD Based on Quantitative CT

间质性肺疾病(ILD)是结缔组织病(CTD)患者常见的并发症和死亡的主要原因。CTD的复杂性给结缔组织病相关间质性肺疾病(CTD-ILD)的诊断与治疗带来了重大挑战，而定量CT在CTD-ILD的诊断、分型、严重程度评估及预后方面展现出潜在应用价值。本文将半定量及定量CT在CTD-ILD中的应用与挑战进行综述，强调定量CT对实现CTD-ILD精准分型、严重程度评估及风险预测的重要性，并对未来研究方向予以展望。Interstitial lung disease (ILD) is a common complication and a major cause of death in patients with connective tissue disease (CTD). The complexity of CTD poses a major challenge in the diagnosis and treatment of connective tissue disease-associated interstitial lung disease (CTD-ILD), and quantitative CT has demonstrated potential applications in the diagnosis, staging, severity assessment and prognosis of CTD-ILD. In this article, we review the applications and challenges of semi-quantitative and quantitative CT in CTD-ILD, emphasise the importance of quantitative CT in achieving accurate typing, severity assessment and risk prediction of CTD-ILD, and provide an outlook on future research directions.