A Rare Case of Adrenocortical Carcinoma in an 8-Year-Old South Asian Male Presented with Hypertensive Encephalopathy and Precocious Puberty

Adrenocortical carcinoma (ACC) represents an inordinately rare malignancy, particularly among children, where its incidence is even more infrequent. The narrow number of firm instances presents challenges in pinpointing prognostic, biological, and therapeutic markers to adapt innovative targeted strategies. Despite the distinction in clinical presentations and pathology, the treatment protocol for childhood ACC typifies that established for adults, occasionally leading to more contentious outcomes. In regions with limited research frameworks and financial restraints interrupting access to modern diagnostic modalities, cases of rare malignancies like pediatric ACC serve as climactic academic and scientific focal territory for further investigation. Presented here is a case of an 8-year-old male from Bangladesh diagnosed with ACC. Surgical intervention was undertaken following imaging studies, and confirmation was received through histopathological examination. However, despite adherence to the protocol-based treatment regimen, the patient succumbed shortly thereafter

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Publication Details

Journal
Scholars Journal of Medical Case Reports
Published
2025-06-18
DOI
https://doi.org/10.36347/sjmcr.2025.v13i06.037
Primary Topic
Adrenal and Paraganglionic Tumors
Type
article
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article

A Rare Case of Adrenocortical Carcinoma in an 8-Year-Old South Asian Male Presented with Hypertensive Encephalopathy and Precocious Puberty

P. B. Biran Roy, D Banik
Scholars Journal of Medical Case Reports
Adrenal and Paraganglionic Tumors
article

A Rare Case of Adrenocortical Carcinoma in an 8-Year-Old South Asian Male Presented with Hypertensive Encephalopathy and Precocious Puberty

P. B. Biran Roy, D Banik
article en

Abstract

Adrenocortical carcinoma (ACC) represents an inordinately rare malignancy, particularly among children, where its incidence is even more infrequent. The narrow number of firm instances presents challenges in pinpointing prognostic, biological, and therapeutic markers to adapt innovative targeted strategies. Despite the distinction in clinical presentations and pathology, the treatment protocol for childhood ACC typifies that established for adults, occasionally leading to more contentious outcomes. In regions with limited research frameworks and financial restraints interrupting access to modern diagnostic modalities, cases of rare malignancies like pediatric ACC serve as climactic academic and scientific focal territory for further investigation. Presented here is a case of an 8-year-old male from Bangladesh diagnosed with ACC. Surgical intervention was undertaken following imaging studies, and confirmation was received through histopathological examination. However, despite adherence to the protocol-based treatment regimen, the patient succumbed shortly thereafter

Scholars Journal of Medical Case ReportsVol. 13(06)
Openalex Percentile: Top 74%
Adrenal and Paraganglionic Tumors
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A Rare Case of Adrenocortical Carcinoma in an 8-Year-Old South Asian Male Presented with Hypertensive Encephalopathy and Precocious Puberty — P. B. Biran Roy, D Banik · Scholars Journal of Medical Case Reports (2025) | TGRS Research Map | TGRS