Efficacy and Safety of Pregabalin for Restless Legs Syndrome in Korean Adults: A Randomized, Double-Blind, Placebo-Controlled Trial
This study failed to demonstrate the therapeutic effect of pregabalin compared with placebo for RLS in Korean adults. Possible reasons for the negative results include low dose, insufficient sample size, and substantial placebo response. Further investigations are warranted to optimize pregabalin therapy in Korean adults with RLS.
Authors
- Jung-Won Shin (ORCID: https://orcid.org/0000-0003-2155-9068)
- Ki‐Young Jung (ORCID: https://orcid.org/0000-0001-5528-9081)
- Jung‐Ick Byun (ORCID: https://orcid.org/0000-0002-6224-4575)
- Jun‐Sang Sunwoo (ORCID: https://orcid.org/0000-0001-8834-0568)
- Yong Won Cho (ORCID: https://orcid.org/0000-0002-6127-1045)
- Won‐Chul Shin (ORCID: https://orcid.org/0000-0003-3044-9397)
Institutions
- Seoul National University Hospital (KR)
- Kangbuk Samsung Hospital (KR)
- CHA University Bundang Medical Center (KR)
- Kyung Hee University Hospital at Gangdong (KR)
- Keimyung University (KR)
Publication Details
- Journal
- Journal of Clinical Neurology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.3988/jcn.2025.0092
- Citations
- 5
- Primary Topic
- Restless Legs Syndrome Research
- Type
- article
- Field-Weighted Citation Impact
- 6.77