MEDFIT-LLM: Medical Enhancements through Domain-Focused Fine Tuning of Small Language Models

This research explores the efficacy of fine-tuning small Large Language Models (LLMs) for AI-based healthcare chatbots. We present a novel approach to dataset creation using synthetic data generation and fine-tuning of various LLMs. The study compares the performance of base models against their fine-tuned counterparts using a carefully curated dataset of healthcare-related questions and answers. Our methodology involves the use of phi 4 for synthetic data generation, supplemented with domain-specific questions derived from existing research. We employ LORA fine-tuning on MLX for four distinct models: Gemma 2 9B 4bit, LLama 3.2 3B Instruct, Mistral 7B, and Qwen2 7B Instruct 8 bit. The results demonstrate the potential of fine-tuning in enhancing the performance of LLMs in specialized healthcare contexts, contributing to the ongoing development of more accurate and reliable AI-powered healthcare chatbots. The code is available at https://github.com/adityak74/medfit-llm.

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Publication Details

Published
2025-05-07
DOI
https://doi.org/10.1109/rmkmate64874.2025.11042816
Citations
1
Primary Topic
Natural Language Processing Techniques
Type
article
Field-Weighted Citation Impact
2.48
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article

MEDFIT-LLM: Medical Enhancements through Domain-Focused Fine Tuning of Small Language Models

Sonam Naidu, Arjun Jaggi, Aditya Karnam Gururaj Rao
1 citations
Natural Language Processing Techniques
2.48
article

MEDFIT-LLM: Medical Enhancements through Domain-Focused Fine Tuning of Small Language Models

Sonam Naidu, Arjun Jaggi, Aditya Karnam Gururaj Rao
article en
1 citations

Abstract

This research explores the efficacy of fine-tuning small Large Language Models (LLMs) for AI-based healthcare chatbots. We present a novel approach to dataset creation using synthetic data generation and fine-tuning of various LLMs. The study compares the performance of base models against their fine-tuned counterparts using a carefully curated dataset of healthcare-related questions and answers. Our methodology involves the use of phi 4 for synthetic data generation, supplemented with domain-specific questions derived from existing research. We employ LORA fine-tuning on MLX for four distinct models: Gemma 2 9B 4bit, LLama 3.2 3B Instruct, Mistral 7B, and Qwen2 7B Instruct 8 bit. The results demonstrate the potential of fine-tuning in enhancing the performance of LLMs in specialized healthcare contexts, contributing to the ongoing development of more accurate and reliable AI-powered healthcare chatbots. The code is available at https://github.com/adityak74/medfit-llm.

Lexicon Pharmaceuticals (United States) (US), HCL Technologies (United States) (US)
Openalex Percentile: Top 10%
Natural Language Processing Techniques
2.48
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MEDFIT-LLM: Medical Enhancements through Domain-Focused Fine Tuning of Small Language Models — Sonam Naidu, Arjun Jaggi, et al. · (2025) | TGRS Research Map | TGRS