Shock index and modified shock index as a predictor of mortality in shock sepsis admitted to the critical care unit

Introduction: Septic shock is characterized by microvascular endothelial dysfunction, dysregulated immune response, and coagulation disorders. Mortality in this state can reach up to 50%. The shock index (SI) is the integration of two physiological variables (heart rate/systolic blood pressure) and modified shock index (MSI) (heart rate/mean arterial pressure); several studies demonstrate it as a predictor of mortality in septic shock. The objective was to determine the prognostic value of the shock index and the modified shock index in patients with septic shock. Material and methods: This was an observational, prospective, and longitudinal study with 176 patients admitted to the critical care unit of Hospital Obrero No. 2, Cochabamba, Bolivia. Results: The study documented that having a SI > 1,1 and an MSI cut-off point of > 1,7 at admission to the critical care unit, presents higher mortality, with a sensitivity CI of 86% (CI: 95%: 0.714-0,869; p = 0,0001), for the MSI a sensitivity of 87% (CI: 95%: 0,722-0.874; p = 0,0001). Discussion: The shock index and modified shock index are moderately accurate predictors of mortality in patients with septic shock admitted to the critical care unit, which could be useful as a reference tool to identify high-risk patients.

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Journal
Health Leadership and Quality of Life
Published
2025-06-20
DOI
https://doi.org/10.56294/hl2025645
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
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article

Shock index and modified shock index as a predictor of mortality in shock sepsis admitted to the critical care unit

Rommer Alex Ortega Martínez, Rafael de Jesús Hernández Zenteno
Health Leadership and Quality of Life
Sepsis Diagnosis and Treatment
article

Shock index and modified shock index as a predictor of mortality in shock sepsis admitted to the critical care unit

Rommer Alex Ortega Martínez, Rafael de Jesús Hernández Zenteno
article en

Abstract

Introduction: Septic shock is characterized by microvascular endothelial dysfunction, dysregulated immune response, and coagulation disorders. Mortality in this state can reach up to 50%. The shock index (SI) is the integration of two physiological variables (heart rate/systolic blood pressure) and modified shock index (MSI) (heart rate/mean arterial pressure); several studies demonstrate it as a predictor of mortality in septic shock. The objective was to determine the prognostic value of the shock index and the modified shock index in patients with septic shock. Material and methods: This was an observational, prospective, and longitudinal study with 176 patients admitted to the critical care unit of Hospital Obrero No. 2, Cochabamba, Bolivia. Results: The study documented that having a SI > 1,1 and an MSI cut-off point of > 1,7 at admission to the critical care unit, presents higher mortality, with a sensitivity CI of 86% (CI: 95%: 0.714-0,869; p = 0,0001), for the MSI a sensitivity of 87% (CI: 95%: 0,722-0.874; p = 0,0001). Discussion: The shock index and modified shock index are moderately accurate predictors of mortality in patients with septic shock admitted to the critical care unit, which could be useful as a reference tool to identify high-risk patients.

Health Leadership and Quality of LifeVol. 4
Ministerio de Salud (BO), Universidad Privada del Valle (BO)
Openalex Percentile: Top 79%
Sepsis Diagnosis and Treatment
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Shock index and modified shock index as a predictor of mortality in shock sepsis admitted to the critical care unit — Rommer Alex Ortega Martínez, Rafael de Jesús Hernández Zenteno · Health Leadership and Quality of Life (2025) | TGRS Research Map | TGRS