Analytical performance of an assay for ergosterol, a potential biomarker for <i>Naegleria fowleri</i> in cerebrospinal fluid
Ergosterol can be reliably detected in spiked human CSF samples and in the supernatant of N fowleri CSF cultures at concentrations of 1.0 to 500 ng/mL. The clinical utility of this method, however, requires further exploration.
Authors
- Christopher D. Doern (ORCID: https://orcid.org/0000-0003-4761-0925)
- Silvia Friedrichs
- Melissa Jamerson (ORCID: https://orcid.org/0000-0002-7577-8066)
- William J. Korzun
Institutions
- Virginia Commonwealth University (US)
- University Health System (US)
- Virginia Commonwealth University Medical Center (US)
Publication Details
- Journal
- Laboratory Medicine
- Published
- 2025-05-21
- DOI
- https://doi.org/10.1093/labmed/lmaf030
- Primary Topic
- Legionella and Acanthamoeba research
- Type
- article
- Field-Weighted Citation Impact
- 0.00