The relationship between polyunsaturated fatty acids and inflammation: evidence from cohort and Mendelian randomization analyses
We find no convincing evidence of a simple pro- and anti-inflammatory dichotomy regarding the function of n-6 and n-3 PUFAs. Further research is needed to better understand the mechanisms underlying the effects of PUFAs on specific immune biomarkers.
Authors
- George Davey Smith (ORCID: https://orcid.org/0000-0002-1407-8314)
- Golam Mohammed Khandaker (ORCID: https://orcid.org/0000-0002-4935-9220)
- Daisy C P Crick (ORCID: https://orcid.org/0000-0001-6659-6626)
- Sarah L. Halligan (ORCID: https://orcid.org/0000-0002-3436-3358)
- Hannah Jones (ORCID: https://orcid.org/0000-0002-5883-9605)
Institutions
- University of Cape Town (ZA)
- Avon and Wiltshire Mental Health Partnership NHS Trust (GB)
- The University of Queensland (AU)
- Stellenbosch University (ZA)
- University Hospitals Bristol NHS Foundation Trust (GB)
- University of Bristol (GB)
- University of Bath (GB)
Publication Details
- Journal
- International Journal of Epidemiology
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1093/ije/dyaf065
- Citations
- 12
- Primary Topic
- Fatty Acid Research and Health
- Type
- article
- Field-Weighted Citation Impact
- 13.44