The Clinical and Molecular Theranostic Roles of Dual Tracer Positron Emission Tomography-Computed Tomography (68Ga-DOTATATE and Fluorodeoxyglucose) and Its Imaging Characteristics in a Patient of Recurrent Glomus Jugulare

Head and neck paragangliomas are rare; among these, glomus jugulare is the second most common. Due to its rarity, close proximity, and adhesion to vital neurovascular structures, treatment of paraganglioma is challenging. Surgery remains the treatment of choice; however, in scenarios of inoperability, molecular theranostics can aid patient management. This case highlights the role of dual-tracer positron emission tomography-computed tomography (PET-CT) imaging, that is, fluorodeoxyglucose (FDG) and somatostatin receptor (SSTR)-based PET-CT imaging with ⁶⁸Gallium-DOTATATE, aiding treatment planning with targeted ¹⁷⁷Lutetium-DOTATATE therapy.

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Journal
Journal of the Association of Physicians of India
Published
2025-05-01
DOI
https://doi.org/10.59556/japi.73.0921
Primary Topic
Adrenal and Paraganglionic Tumors
Type
article
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article

The Clinical and Molecular Theranostic Roles of Dual Tracer Positron Emission Tomography-Computed Tomography (68Ga-DOTATATE and Fluorodeoxyglucose) and Its Imaging Characteristics in a Patient of Recurrent Glomus Jugulare

Sunita Sonavane, Sandip Kanti Basu, Yoga S. Narwadkar
Journal of the Association of Physicians of India
Adrenal and Paraganglionic Tumors
article

The Clinical and Molecular Theranostic Roles of Dual Tracer Positron Emission Tomography-Computed Tomography (68Ga-DOTATATE and Fluorodeoxyglucose) and Its Imaging Characteristics in a Patient of Recurrent Glomus Jugulare

Sunita Sonavane, Sandip Kanti Basu, Yoga S. Narwadkar
article en

Abstract

Head and neck paragangliomas are rare; among these, glomus jugulare is the second most common. Due to its rarity, close proximity, and adhesion to vital neurovascular structures, treatment of paraganglioma is challenging. Surgery remains the treatment of choice; however, in scenarios of inoperability, molecular theranostics can aid patient management. This case highlights the role of dual-tracer positron emission tomography-computed tomography (PET-CT) imaging, that is, fluorodeoxyglucose (FDG) and somatostatin receptor (SSTR)-based PET-CT imaging with ⁶⁸Gallium-DOTATATE, aiding treatment planning with targeted ¹⁷⁷Lutetium-DOTATATE therapy.

Journal of the Association of Physicians of IndiaVol. 73(5)
Homi Bhabha National Institute (IN)
Good health and well-being
Openalex Percentile: Top 75%
Adrenal and Paraganglionic Tumors
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