National Consensus Statement on Role of Bisoprolol across Cardiovascular Continuum: Special Focus on Women
Cardiovascular diseases (CVDs) represent a significant health concern worldwide, with women facing distinct challenges in the prevention, diagnosis, and management of these conditions. In India, hypertension is a prevalent cardiovascular (CV) risk factor, affecting nearly one-third of adults, and women experience a disproportionately high burden across all age-groups. The CV continuum, which spans from risk factors to CV events and ultimately to heart failure (HF), demonstrates how the progression of CVD impacts women at each stage differently due to gender-specific mechanisms like hormonal influences, pregnancy complications and the effects of menopause. This manuscript aims to present a set of consensus statements developed by an expert panel in India, focusing on the role of bisoprolol across the CV continuum with special attention to women. The consensus was formed based on a thorough review of clinical experiences, existing clinical data and alignment with both global and regional clinical guidelines. The manuscript highlights the gender-specific CV risks faced by women, their higher mortality rates following acute cardiac events, delayed diagnoses and less aggressive treatments. It also discusses bisoprolol as an effective therapy for managing hypertension, HF and other CV conditions in women. Bisoprolol's benefits include consistent blood pressure (BP) control, improved outcomes in HF and reduced CV risks, particularly in postmenopausal women and those with comorbidities. The manuscript underscores the need for gender-tailored approaches to the CV continuum, from prevention through to management, to address these challenges and improve outcomes for women.
Authors
- Mohit Tyagi (ORCID: https://orcid.org/0000-0001-9524-3109)
- Hardeep Singh Malhotra (ORCID: https://orcid.org/0000-0003-0438-4446)
- Rishi Sethi (ORCID: https://orcid.org/0000-0002-6745-6235)
- Asha Mahilmaran
- Gyarsi Lal Sharma
- Dorairaj Prabhakaran (ORCID: https://orcid.org/0000-0002-3172-834X)
- Showkat Ul Nabi (ORCID: https://orcid.org/0000-0002-0754-6722)
- G. Justin Paul (ORCID: https://orcid.org/0000-0002-8588-5594)
- Hetan Shah (ORCID: https://orcid.org/0000-0001-7954-2424)
- Triloki Singh
- Yatin Mehta (ORCID: https://orcid.org/0000-0002-0888-4774)
- Chandrashekhar K. Ponde
- Shishu Mishra
- Aditya Kapoor (ORCID: https://orcid.org/0000-0002-2539-2675)
- Syed Sahajada Mahafujul Alam (ORCID: https://orcid.org/0000-0001-8439-1923)
- Vanita Arora (ORCID: https://orcid.org/0000-0003-1025-9609)
- Sarita Rao (ORCID: https://orcid.org/0009-0008-5363-8952)
- Akash Gujral (ORCID: https://orcid.org/0000-0003-4250-9086)
- Ashwani Mehta (ORCID: https://orcid.org/0009-0006-3135-7303)
- Manish Aggarwal (ORCID: https://orcid.org/0000-0002-3613-644X)
- Ameet Sattur
- Pravin M Bhat (ORCID: https://orcid.org/0000-0003-3666-1479)
- Anu Grover (ORCID: https://orcid.org/0000-0002-6396-1744)
- Samir Kubba (ORCID: https://orcid.org/0000-0003-0851-4017)
- Ramesh Hotchandani
- Pawan Kumar Mangla
- Dinesh Khullar (ORCID: https://orcid.org/0000-0003-4276-2575)
- Manisha Sahay (ORCID: https://orcid.org/0000-0001-5534-2516)
- Vijay Kumar Garg (ORCID: https://orcid.org/0000-0001-9914-5266)
- Lovelina Singh (ORCID: https://orcid.org/0000-0002-9577-859X)
- Sandeep Bhalla (ORCID: https://orcid.org/0000-0001-9027-0001)
- Harjeet Singh (ORCID: https://orcid.org/0000-0002-0748-9473)
- Sanjay Sood (ORCID: https://orcid.org/0000-0002-7358-5228)
- Makarand Paithankar
- Alok Kumar (ORCID: https://orcid.org/0000-0003-3887-0733)
- Ajay Sinha (ORCID: https://orcid.org/0000-0001-5201-7718)
- Ravindra Kumar Garg (ORCID: https://orcid.org/0000-0003-0044-7083)
- Tripti Deb
- Yashita Arora (ORCID: https://orcid.org/0009-0005-0458-5135)
- Ritesh Sanguri
- Asha Moorthy
- Rajeev Rajput
- Poonam Malhotra (ORCID: https://orcid.org/0000-0003-3342-1314)
- Ashok K Omar
- Rajeev Agarwala
- Preeti Gupta (ORCID: https://orcid.org/0000-0001-6261-4938)
- Rekha Mishra
- Vishal Rastogi (ORCID: https://orcid.org/0000-0003-0323-3371)
- Ish Kalra
- Tiny Nair (ORCID: https://orcid.org/0000-0001-9243-281X)
- Shanthy Sundaram (ORCID: https://orcid.org/0000-0001-5162-9114)
- Saurabh Bagga
- Shibba Takkar Chhabra (ORCID: https://orcid.org/0000-0002-3842-1527)
- Viren Kaul (ORCID: https://orcid.org/0000-0003-3047-4840)
- Rohit Tandon (ORCID: https://orcid.org/0000-0001-7879-6262)
- Inam Danish Khan (ORCID: https://orcid.org/0000-0002-9824-8711)
- V K Katyal (ORCID: https://orcid.org/0000-0002-3044-6914)
- Vivudh Pratap Singh (ORCID: https://orcid.org/0000-0001-9539-1734)
- Mona Bhatia (ORCID: https://orcid.org/0000-0001-8988-4997)
- Zakia Khan
- Hriday Kumar Chopra
- Sumit Sethi
- Madan L. Arora
- Anil Dhall (ORCID: https://orcid.org/0009-0007-3774-4184)
- Nitish Parmar (ORCID: https://orcid.org/0000-0003-0953-8176)
- Vipul Rastogi (ORCID: https://orcid.org/0009-0007-9073-1091)
- Geeta Sheth
- Navin C. Nanda (ORCID: https://orcid.org/0000-0002-9657-5620)
- Rohini Handa (ORCID: https://orcid.org/0000-0001-6685-4170)
- Manju Hotchandani
- K. Sood (ORCID: https://orcid.org/0000-0001-8123-9002)
- Prachi Garg (ORCID: https://orcid.org/0000-0003-1642-4986)
- Kapil Kumar
- Ruchi Verma
- Rohit Singla (ORCID: https://orcid.org/0000-0001-5823-0288)
- Pradeep Kumar Jain (ORCID: https://orcid.org/0000-0003-2581-5890)
- Ravi Prakash (ORCID: https://orcid.org/0000-0003-4604-1759)
- Atul Sharma (ORCID: https://orcid.org/0000-0002-8960-5449)
- Ahsan Khan
- Saumitra Ray
- L. Raj (ORCID: https://orcid.org/0000-0003-0913-522X)
- Atul Abhyankar (ORCID: https://orcid.org/0000-0002-9726-1359)
- Uttara Das (ORCID: https://orcid.org/0000-0002-0303-1203)
- Sajal Gupta
- Vitull Kumar Gupta (ORCID: https://orcid.org/0009-0005-3146-0098)
- Anil Kumar Bhalla
- Dharmender Jain
- Vikas Agrawal
- Sarita Bajaj
- Naveen Garg
- A K Bali
- Suri Niranjan
- J.P.S. Sawhney
- Rajiv Passey
- Mohan Bhargava
- S. Nithya Kalyani
- Anupam Goel
- S. Chooramani Gopal
- Ajay Mahajan
- Sonia Rawat
- Vinod Mittal
- S. Pathak
- Suchita Arora
- R. Mehrotra
- Hem K Tewari
- Vivek Tandon
- Rahul Ramdas Ramteke
- A K Pancholia
- Kavita Tyagi
- Sangeeta Chaudhary
- Sandeep Sharma (ORCID: https://orcid.org/0009-0006-3809-3910)
- Nilakshi Deka
- Veena Bhat
- Sanjay Porwal
- Kamal Kumar Sethi
- Ish Kathpalia
- Kiran Kukreja
- Satya Naryana
- Upadhyayula Satyanarayan
- Satya Narayan Rautray
- Ishwarappa Balekundri Vijaylakshami
- Chandra Mukhi
- Cecily Majella
- Shakuntala Dawesar
- Bhushan K Dawesar
- Manoj Pabrai
- Anupama Kathpalia
Institutions
- Handan College (CN)
- Medanta The Medicity (IN)
- Indraprastha Apollo Hospitals (IN)
- Safdarjang Hospital (IN)
- Apollo Hospitals (IN)
- Defence Research and Development Organisation (IN)
- Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (IN)
- Shri Venkateshwara University (IN)
- Madras Medical College (IN)
- Sanjay Gandhi Post Graduate Institute of Medical Sciences (IN)
- Grant Medical College and Sir Jamshedjee Jeejeebhoy Group of Hospitals (IN)
- Indian Oil Corporation (India) (IN)
- Indian Council of Agricultural Research (IN)
- Vardhman Mahavir Medical College & Safdarjung Hospital (IN)
- King Edward Memorial Hospital and Seth G.S. Medical College (IN)
- Fortis Healthcare (IN)
- Almas Hospital (IN)
- Lokmanya Tilak Municipal General Hospital and Lokmanya Tilak Municipal Medical College (IN)
- P. D. Hinduja Hospital and Medical Research Centre (IN)
- Aware Global Hospital (IN)
- Osmania General Hospital (IN)
- Billroth Hospitals (IN)
- Max Super Speciality Hospital (IN)
- CARE Hospitals (IN)
- London Chest Hospital (GB)
- Sri Jayadeva Institute of Cardiovascular Sciences and Research (IN)
- King George's Medical University (IN)
- Motilal Nehru Medical College (IN)
- Max Healthcare (IN)
- Shree Guru Gobind Singh Tricentenary University (IN)
- Sriram Chandra Bhanja Medical College Hospital (IN)
- University of Alabama at Birmingham (US)
- Dayanand Medical College & Hospital (IN)
- Midas Multispeciality Hospital (IN)
- Society of Interventional Radiology (US)
- The Coordinating Center (US)
- Diabetes Care and Research Foundation (IN)
- India Diabetes Research Foundation (IN)
- National Heart Institute (IN)
- Care India (IN)
- Fortis Escorts Heart Institute (IN)
- Jawaharlal Nehru Medical College (IN)
- Sri Ramachandra Medical Centre (IN)
- Sir Ganga Ram Hospital (IN)
- HCG Cancer Hospital (IN)
- Jaswant Rai Speciality Hospital (IN)
- Medanta The Medicity (IN)
- Sitaram Bhartia Institute of Science and Research (IN)
- Cancer Hospital and Research Institute (IN)
- Programme on Women’s Economic, Social and Cultural Rights (IN)
- Fortis Hospital (IN)
- RED Consulting (Norway) (NO)
- Mother Hospital (IN)
- Fortis Escorts Hospital (IN)
- Apollo Hospitals (IN)
- Pain Clinic of India (IN)
- Diabetes Foundation (IN)
- Sant Parmanand Hospital (IN)
- Healthcare Global Enterprises (IN)
- Institute of Cardiology (PL)
- Shri Vishwakarma Skill University (IN)
- Batra Hospital and Medical Research Centre (IN)
- Respiratory Clinical Trials (AU)
- Ophthalmology Clinic (DE)
- Nethradhama Superspeciality Eye Hospital (IN)
- Public Works Department Buildings and Roads (IN)
- Ministry of Defence (IN)
- Fortis Hospital (IN)
- Apollo Hospitals (IN)
- Associated Radiologists (US)
- Choithram Hospital and Research Centre (IN)
- Command Hospital (IN)
- Sir Ganga Ram Hospital (PK)
- Artemis Hospitals (IN)
- Rajasthan Dental College and Hospital (IN)
- SingularLogic (Greece) (GR)
- AMRI Hospitals (IN)
- All India Institute of Medical Sciences (IN)
- American Congress of Obstetricians and Gynecologists (US)
- Banaras Hindu University (IN)
Publication Details
- Journal
- Journal of the Association of Physicians of India
- Published
- 2025-05-01
- DOI
- https://doi.org/10.59556/japi.73.0957
- Citations
- 1
- Primary Topic
- Heart Failure Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.39