The immunological and histological effects of the leaves and fruits of the sea buckthorn plant in hepatitis rats.

Objectives: This study aimed to establish the immunological and histological effects of the leaves and fruits of the sea buckthorn plant on hepatotoxic rats. Materials and Methods: Thirty-six healthy male Sprague Dawley rats were split into six groups, each comprising six mice. a negative control (C -ve) for normal mice. The mice in the remaining groups (number = 30) received injections of CCl4. All mice were separated into five groups: four groups received BL (5% and 10%) and BF (5% and 10%), while one group served as a positive control (C+ve) that exhibited the sickness but did not adhere to the experimental diet. Results : The maximum RBCs concentration of group’s receiving treatment was noted for hepatointoxicated Group"4 " (rats nourished on 10% BL). While the smallest value was noted for Group"5 " (rats nourished on five percent BF) with significant variance (P-value below 0.05). Conversely, the greatest WBCs level of group receiving treatment noted for hepatointoxicated group rats nourished on 5% (BF). While the minimal value noted for hepatointoxicated group rats nourished on 10 % BL) with non-significant distinction (P-value below 0.05) .