Prospective multicenter validation of preoperative plasma ceramides as novel predictive biomarkers for clinically relevant post-hepatectomy liver failure

Plasma CER(d18:1/20:1) is a novel predictor of CR-PHLF. The Hpx-CER model performs commendably in predicting CR-PHLF and provides reliable preoperative risk estimations.

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Publication Details

Journal
International Journal of Surgery
Published
2025-06-24
DOI
https://doi.org/10.1097/js9.0000000000002791
Primary Topic
Sphingolipid Metabolism and Signaling
Type
article
Field-Weighted Citation Impact
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article

Prospective multicenter validation of preoperative plasma ceramides as novel predictive biomarkers for clinically relevant post-hepatectomy liver failure

Shiyu Lin, Hanbiao Liang, Baoxiong Zhuang, Jieyuan Li et al.
International Journal of Surgery
Sphingolipid Metabolism and Signaling
article

Prospective multicenter validation of preoperative plasma ceramides as novel predictive biomarkers for clinically relevant post-hepatectomy liver failure

Shiyu Lin, Hanbiao Liang, Baoxiong Zhuang, Jieyuan Li, Leyi Liao, Cuiting Liu, Weiyi Guo, Bowen Zhu, Chuanjiang Li, Can Huang, Shanhua Tang, Kai Wang, Biao Wang, Qifan Zhang, Jing Gao, Jie Zhou, Qingping Li, Jianping Qian, Minghui Zeng, Xuesong Deng, Tianzhou Peng, Zhanhong Lai, Pengxiang Huang, Xianqiu Wu, Haiqing Liu
article en

Abstract

Plasma CER(d18:1/20:1) is a novel predictor of CR-PHLF. The Hpx-CER model performs commendably in predicting CR-PHLF and provides reliable preoperative risk estimations.

International Journal of SurgeryVol. 111(10)
Southern University of Science and Technology (CN), Nanfang Hospital (CN), First People's Hospital of Foshan (CN), Dongguan People’s Hospital (CN), Shenzhen University Health Science Center (CN), Shenzhen Second People's Hospital (CN), Shenzhen Third People’s Hospital (CN), Southern Medical University (CN)
Peace, Justice and strong institutions
Openalex Percentile: Top 87%
Sphingolipid Metabolism and Signaling
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