Large Seminoma in a Reproductive-Age Woman with Complete Androgen Insensitivity Syndrome: A Case Report

Complete Androgen insensitivity Syndrome (CAIS) is a disorder of androgen hormone resistance characterized by female phenotypes in individuals with XY karyotype. The typical clinical feature for CAIS is primary amenorrhea in adolescents, or inguinal swelling in infants. Women with this disorder have breast development and puberty growth at an appropriate age, but not menstruation. In this paper reported cases of women aged 38 years came with complaints of an enlarged lump in the left inguinal since 10 years. During his life the patient has never experienced menstruation. The lump in the patient is then removed, histological examination is performed, and a semimoma feature is obtained. The karyotype examination is performed and shows the XY sex chromosome.

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Publication Details

Journal
International Journal of Social health
Published
2025-06-07
DOI
https://doi.org/10.58860/ijsh.v4i5.305
Primary Topic
Testicular diseases and treatments
Type
article
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article

Large Seminoma in a Reproductive-Age Woman with Complete Androgen Insensitivity Syndrome: A Case Report

Achmad Kemal Harzif, Kristian Alda
International Journal of Social health
Testicular diseases and treatments
article

Large Seminoma in a Reproductive-Age Woman with Complete Androgen Insensitivity Syndrome: A Case Report

Achmad Kemal Harzif, Kristian Alda
article en

Abstract

Complete Androgen insensitivity Syndrome (CAIS) is a disorder of androgen hormone resistance characterized by female phenotypes in individuals with XY karyotype. The typical clinical feature for CAIS is primary amenorrhea in adolescents, or inguinal swelling in infants. Women with this disorder have breast development and puberty growth at an appropriate age, but not menstruation. In this paper reported cases of women aged 38 years came with complaints of an enlarged lump in the left inguinal since 10 years. During his life the patient has never experienced menstruation. The lump in the patient is then removed, histological examination is performed, and a semimoma feature is obtained. The karyotype examination is performed and shows the XY sex chromosome.

International Journal of Social healthVol. 4(5)
University of Indonesia (ID), Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo (ID)
Openalex Percentile: Top 75%
Testicular diseases and treatments
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Large Seminoma in a Reproductive-Age Woman with Complete Androgen Insensitivity Syndrome: A Case Report — Achmad Kemal Harzif, Kristian Alda · International Journal of Social health (2025) | TGRS Research Map | TGRS