Association between polygenic risk scores for hypertension and low-density lipoprotein cholesterol with incident chronic kidney disease
This study showed that individuals with a higher genetic predisposition to HTN were more likely to develop CKD than those predisposed to a high LDL-C concentration. Additionally, higher genetic predispositions for these two factors did not synergically contribute to the risk of CKD.
Authors
- Shin‐Wook Kang (ORCID: https://orcid.org/0000-0002-5677-4756)
- Hee Byung Koh (ORCID: https://orcid.org/0000-0002-4510-2823)
- Seung Hyeok Han (ORCID: https://orcid.org/0000-0001-7923-5635)
- Ga Young Heo (ORCID: https://orcid.org/0000-0003-0913-5289)
- Tae Ik Chang (ORCID: https://orcid.org/0000-0003-3311-6379)
- Tae‐Hyun Yoo (ORCID: https://orcid.org/0000-0002-9183-4507)
- Cheol Ho Park (ORCID: https://orcid.org/0000-0003-4636-5745)
- Hyung Woo Kim (ORCID: https://orcid.org/0000-0002-6305-452X)
- Jung Tak Park (ORCID: https://orcid.org/0000-0002-2325-8982)
- Byounghwi Ko (ORCID: https://orcid.org/0009-0007-9056-8503)
- Donna Kang (ORCID: https://orcid.org/0000-0003-0466-3664)
Institutions
- Yonsei University (KR)
- National Health Insurance Service Ilsan Hospital (KR)
- Catholic Kwandong University International St. Mary's Hospital (KR)
- National Health Insurance Service (KR)
Publication Details
- Journal
- Kidney Research and Clinical Practice
- Published
- 2025-06-16
- DOI
- https://doi.org/10.23876/j.krcp.24.255
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Yonsei University
- Yonsei University College of Medicine