Industry Sponsorship and Research Outcomes in A Sample of Landmark Ophthalmology Trials
Among pivotal ophthalmology trials, industry sponsorship was associated with results and conclusions that favoured investigational products compared to non-industry sponsored trials. This disparity was not comprehensively explained by the commonly used RoB2 tool, since both groups did not significantly differ over most domains. Our results support need for transparent research practices and continued critical appraisal of the existing trial literature.
Authors
- Radha P. Kohly (ORCID: https://orcid.org/0000-0002-1355-6599)
- Brendan Tao (ORCID: https://orcid.org/0000-0001-7069-3162)
- Marko M. Popovic (ORCID: https://orcid.org/0000-0002-0370-5968)
- Edward Margolin (ORCID: https://orcid.org/0000-0002-6738-7225)
- Thanansayan Dhivagaran (ORCID: https://orcid.org/0000-0003-0571-2894)
- Fahad Butt
Institutions
- Western University (CA)
- University of Toronto (CA)
- Southern California Eye Institute (US)
Publication Details
- Journal
- American Journal of Ophthalmology
- Published
- 2025-06-25
- DOI
- https://doi.org/10.1016/j.ajo.2025.06.037
- Citations
- 2
- Primary Topic
- Pharmaceutical industry and healthcare
- Type
- article
- Field-Weighted Citation Impact
- 3.11