To Evaluate The Effectiveness Of Non-Pharmacological Multifactorial Interventions On Cognitive Impairment In Geriatric Patients

This prospective, cohort study was planned to assess the efficacy of nonpharmacological multifactorial approach for treating cognitive decline in patients of geriatric age group. This research involved 120 patients and caregivers, ≥ 65 years, with cognitive impairment, was a consecutive sample from a tertiary hospital. Measures involved learning and problem solving tasks, motor movement, company, and food choices that addressed participants' requirements. Cognitive status was evaluated by MMSE and MoCA, physical performance measured with TUG, depression with GDS and nutritional status with BMI and blood sample. Subsequent evaluations were done at 3 month interval for 1 year. At the end of 12 months, improvement in cognitive function was noted by a mean of 4.0 points in MMSE, and mean of 3.8 points in MoCA. Physical fitness, depression status, nutritional status, social integration and sleep quality were also found to have significant changes across time. Also, the studies revealed an enhancement of patients' satisfaction as well as a reduction in caregiver burden. These results raise the possibility that approaches targeting multiple risk factors of cognitive decline can effectively promote cognitive function and general quality of life in elderly people.

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Publication Details

Journal
Pakistan Journal of Pharmaceutical Sciences
Published
2025-01-01
DOI
https://doi.org/10.36721/pjps.2025.38.3.reg.13870.1
Primary Topic
Health and Well-being Studies
Type
article
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article

To Evaluate The Effectiveness Of Non-Pharmacological Multifactorial Interventions On Cognitive Impairment In Geriatric Patients

Jiajia Cui, Junjun Zhu, Yanbin Wei, Quanjun Piao
Pakistan Journal of Pharmaceutical Sciences
Health and Well-being Studies
article

To Evaluate The Effectiveness Of Non-Pharmacological Multifactorial Interventions On Cognitive Impairment In Geriatric Patients

Jiajia Cui, Junjun Zhu, Yanbin Wei, Quanjun Piao
article en

Abstract

This prospective, cohort study was planned to assess the efficacy of nonpharmacological multifactorial approach for treating cognitive decline in patients of geriatric age group. This research involved 120 patients and caregivers, ≥ 65 years, with cognitive impairment, was a consecutive sample from a tertiary hospital. Measures involved learning and problem solving tasks, motor movement, company, and food choices that addressed participants' requirements. Cognitive status was evaluated by MMSE and MoCA, physical performance measured with TUG, depression with GDS and nutritional status with BMI and blood sample. Subsequent evaluations were done at 3 month interval for 1 year. At the end of 12 months, improvement in cognitive function was noted by a mean of 4.0 points in MMSE, and mean of 3.8 points in MoCA. Physical fitness, depression status, nutritional status, social integration and sleep quality were also found to have significant changes across time. Also, the studies revealed an enhancement of patients' satisfaction as well as a reduction in caregiver burden. These results raise the possibility that approaches targeting multiple risk factors of cognitive decline can effectively promote cognitive function and general quality of life in elderly people.

Pakistan Journal of Pharmaceutical SciencesVol. 38(3)
Lishui City People's Hospital (CN)
Zero hunger
Openalex Percentile: Top 79%
Health and Well-being Studies
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