Adrenomedullin as an Immunomodulator of CD14<sup>+</sup>MerTK<sup>+</sup> Circulating Monocytes in Liver Failure Syndromes
ADM is increased in liver failure, whereas AMBP1 is reduced. ADM affects monocyte function, increasing Mer Tyrosine Kinase and promoting a pro-restorative, anti-inflammatory phenotype.
Authors
- Stephen R. Atkinson (ORCID: https://orcid.org/0000-0002-6910-7100)
- Florent Artru (ORCID: https://orcid.org/0000-0002-2220-6646)
- Joseph Wilson
- Mark McPhail (ORCID: https://orcid.org/0000-0001-5449-2424)
- Roosey Sheth
- Francesca M. Trovato (ORCID: https://orcid.org/0000-0002-8048-1646)
- John Smith (ORCID: https://orcid.org/0009-0004-3564-6052)
- Rima Abdalla
- Anna Broderick
Institutions
- King's College London (GB)
- King's College Hospital (GB)
- Imperial College London (GB)
Publication Details
- Journal
- Journal of Clinical and Translational Hepatology
- Published
- 2025-06-24
- DOI
- https://doi.org/10.14218/jcth.2025.00074
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- King's College London
- Medical Research Council