Autoimmune glial fibrillary acidic protein astrocytopathy suspected of intracranial infection: A case report

Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) is an autoimmune-mediated neurological disease with cerebrospinal fluid GFAP-IgG as a marker. This is a rare disease. This paper reported a GFAP-A patient suspected intracranial infection whose diagnosis and treatment were summarized, and the value of negative metagenomic second-generation sequencing (mNGS) results for the exclusion of infectious diseases and the preferred treatment plan for GFAP-A were discussed.