Neuroprotective Proteins in Hypoxia-stressed Astrocyte-Derived Extracellular Vesicles
The present study makes a novel contribution by employing proteomic techniques to characterize the protein cargo of EVs isolated from primary rat astrocytes. This approach enables a more refined analysis of astrocyte-specific intercellular signaling under hypoxic conditions and provides valuable insights into the roles of astrocytes in maintaining brain homeostasis and contributing to pathological processes.
Authors
- Luis B. Tovar‐y‐Romo (ORCID: https://orcid.org/0000-0003-2605-1378)
- Manuel Santos Gutiérrez (ORCID: https://orcid.org/0000-0001-8617-2804)
- Elton A. S. Castro (ORCID: https://orcid.org/0000-0003-1802-912X)
- Isaac Ponce (ORCID: https://orcid.org/0000-0001-6587-2983)
- B. Vicente
Institutions
- National Institute of Genomic Medicine (MX)
- Weizmann Institute of Science (IL)
- Instituto Politécnico Nacional (MX)
- Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (MX)
- Universidad Nacional Autónoma de México (MX)
Publication Details
- Journal
- Current Neuropharmacology
- Published
- 2025-06-24
- DOI
- https://doi.org/10.2174/011570159x359837250611052037
- Citations
- 4
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 3.22