Comparative evaluation of four commercial analyzers for the serological screening of hepatitis A

This study highlights inter-assay variability in anti-HAV IgM detection and underscores the need for improved harmonization across platforms. Future studies incorporating a sufficient number of molecularly confirmed acute hepatitis A cases are warranted to clarify the causes of false results and minimize the potential clinical impact of inaccurate testing.

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Publication Details

Journal
Virology Journal
Published
2025-06-24
DOI
https://doi.org/10.1186/s12985-025-02770-2
Primary Topic
Hepatitis Viruses Studies and Epidemiology
Type
article
Field-Weighted Citation Impact
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article

Comparative evaluation of four commercial analyzers for the serological screening of hepatitis A

Junhyup Song, Sinyoung Kim, Younhee Park, Jiyeon Kim
Virology Journal
Hepatitis Viruses Studies and Epidemiology
article

Comparative evaluation of four commercial analyzers for the serological screening of hepatitis A

Junhyup Song, Sinyoung Kim, Younhee Park, Jiyeon Kim
article en

Abstract

This study highlights inter-assay variability in anti-HAV IgM detection and underscores the need for improved harmonization across platforms. Future studies incorporating a sufficient number of molecularly confirmed acute hepatitis A cases are warranted to clarify the causes of false results and minimize the potential clinical impact of inaccurate testing.

Virology JournalVol. 22(1)
Yonsei University (KR), Severance Hospital (KR)
Good health and well-being
Openalex Percentile: Top 79%
Hepatitis Viruses Studies and Epidemiology
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