Role of the clock gene homolog aha-1 in the circadian system of Caenorhabditis elegans
The results indicate that the CYCLE/BMAL-1 homolog AHA-1 plays a key role in the generation of circadian rhythms in adult nematodes, mainly by regulating period length. These results suggest that the molecular control of circadian regulation in <i>C. elegans</i> exhibits some similarities to other clock model systems.
Authors
- Diego A. Golombék (ORCID: https://orcid.org/0000-0002-6291-5586)
- Melisa L. Lamberti
- Claire Y. Bénard (ORCID: https://orcid.org/0000-0002-1919-1877)
- María Laura Migliori
- María Eugenia Goya (ORCID: https://orcid.org/0000-0002-5031-2470)
- Francisco Silva (ORCID: https://orcid.org/0000-0003-0904-6243)
Institutions
- National University of Quilmes (AR)
- Université du Québec à Montréal (CA)
- University of San Andrés (AR)
- Dialyse Centrum Groningen (NL)
- 123 Certification (Canada) (CA)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2025-06-24
- DOI
- https://doi.org/10.3389/fnins.2025.1618370
- Citations
- 1
- Primary Topic
- Circadian rhythm and melatonin
- Type
- article
- Field-Weighted Citation Impact
- 0.91
Funders
- Consejo Nacional de Investigaciones Científicas y Técnicas
- Universidad Nacional de Quilmes
- Agencia Nacional de Promoción de la Investigación, el Desarrollo Tecnológico y la Innovación
- National Institutes of Health
- Fondo para la Investigación Científica y Tecnológica